Article on Glutamine What is Glutamine Glutamine as an amino acid used in nutrition therapy. It is also being studied for the treatment of diarrhea caused by radiation therapy to the pelvis. One of 20 amino acids. People with Huntington have more glutamines in the huntingtin protein because of the increased number of CAG repeats. Glutamine crystalline amino acid occurring in proteins important in protein metabolism. Glutamine (molecular weight: 146.15 g/mol) is one of the 20 amino acids encoded by the genetic code. Its side chain is an amide it is formed by replacing a side-chain hydroxyl of glutamic acid with an amine functional group.
What Glutamine Can do for Body: 1 - A non-essential amino acid, glutamine is considered to be a brain fuel. Glutamine has been used therapeutically for alcoholism, mild depression and to reduce the craving for sweets. Glutamine is very important in the functioning of the metabolism and muscle maintenance. Glutamine supplementation can help prevent muscle and other tissue breakdown by providing the body with nitrogen and fuel.
2 - An amino acid that is part of the huntingtin protein. In Huntington's Disease, the defective gene causes an excessive number of glutamine amino acids to be inserted in the huntingtin protein that is made.
3 - Glutamine is a supplement that is used in weightlifting and bodybuilding, as well as by those who suffer for muscular cramps or pain—particularly elderly people.
4 - The main use of glutamine within the diet of either groups is as a means of replenishing the body's stores of amino acids that have been used during exercise or everyday activities.
5 - However, normal supplementation is healthy mainly because glutamine is supposed to be supplemented after prolonged periods of exercise (for example, a workout or exercise in which amino acids are required for use) and replenishes amino acid stores this being the main reason glutamine is recommended during fasting or for people who suffer from physical trauma, immune deficiencies, or cancer.
6 - there is now a significant body of evidence that links glutamine-enriched diets with intestinal effects aiding maintenance of gut barrier function, intestinal cell proliferation and differentiation, as well as generally reducing septic morbidity.
7 - The reason for such "cleansing" properties is thought to stem from the fact that the intestinal extraction rate of glutamine is higher than that for other amino acids, and is therefore thought to be the most viable option when attempting to alleviate conditions relating to the gut.
8 - It is also known that glutamine has various effects in reducing healing time after operations. Hospital waiting times after abdominal surgery are reduced by providing parenteral nutrition regimens containing amounts of glutamine to patients.
Glutamine peptides:
Increase hGF levels and promotes muscle growth. It’sa powerful recovery agent with excellent absorption, and supplies critical building blocks for more muscle.
Glutamine repeats:
These are additional repeats of the amino acid glutamine, which when joined to proteins, increase the risk of soluble proteins folding into insoluble ß-pleated sheets. They are commonly found on huntingtin, the abnormal protein found in Huntingdon's disease.
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